Spravato is only available at certified treatment centers. Here’s how to find one near you, what to ask, and what to expect.
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Spravato (esketamine) nasal spray can only be given at clinics certified in the Spravato REMS program, where you take the dose under supervision and stay for at least two hours of monitoring. It is never dispensed for use at home.
In Arizona, most certified clinics are in the Phoenix metro area, with others in Tucson and smaller numbers in Northern Arizona. Because treatment starts with two visits a week, the right clinic is usually one that’s close enough to reach easily and in network with your plan.
By area: Phoenix · Tucson · Flagstaff & Sedona · Prescott
A typical schedule, based on the FDA label. Your prescriber may adjust it.
Usually two sessions a week. Each visit includes the dose plus at least two hours of monitoring in the clinic.
Usually once a week, depending on how you’re responding.
Weekly or every two weeks, as your prescriber recommends.
You can’t drive until the next day after a restful sleep, so plan a ride for each session.
Checking coverage? Is Spravato covered by insurance?
Sources: FDA Spravato prescribing information and REMS program requirements (2025); Janssen Spravato treatment center information (spravato.com).
Clear answers to the questions people ask before choosing a clinic.
Spravato is only given at REMS-certified treatment centers. You can use the official treatment center finder at spravato.com, ask your psychiatrist, or schedule a free Same Team navigation call and we’ll help you find a clinic that fits your location and insurance.
Adults with treatment-resistant depression — usually meaning at least two antidepressants haven’t worked well enough — or major depressive disorder with acute suicidal thoughts or behavior. A licensed prescriber decides whether it’s right for you.
Plan for two to three hours. After each dose you’re monitored in the clinic for at least two hours.
No. The FDA label says not to drive or operate machinery until the next day after a restful sleep.
Usually, for eligible patients with prior authorization. That includes most commercial plans, Medicare Part B, AHCCCS plans, and Tricare. See our Spravato insurance guide for details by insurer.
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